Hongyue Dai, PhD
Vice President, Bioinformatics, Cygnal Therapeutics
Hongyue Dai joined Cygnal Therapeutics as Vice President of Bioinformatics. He formerly served as CSO and CBIO at M2Gen where he helped build the ORIEN, a cancer center network, connecting cancer hospitals with pharma companies for cancer research and drug development. While at M2Gen, he filed more than 10 patents on cancer prognosis models covering various cancer types.
Hongyue also served as Executive Director of Informatics & Analysis in Discovery & Preclinical Sciences of Merck Research Labs. He managed genomics and genetics projects to support all therapeutic franchises for target identification, biomarker discovery, compound prioritization and translating biomarkers in clinical trials.
Prior to Merck, Hongyue was Research Associate Professor of the Physics Department at the University of Utah where he analyzed and defended the highest energy cosmic ray particle (https://en.wikipedia.org/wiki/Oh-My-God_particle). He then took on the role as a senior data analyst at Rosetta where he co-developed the first microarray data error model to characterize the data uncertainty. He made significant contributions to the first FDA approved multi-gene test kit for breast cancer prognosis, the MammaPrint. He also collaborated with Celera to develop the 14-gene test kit for ER-positive breast cancer patients.
Hongyue received his undergraduate degree from Peking University and Ph.D. from the Institute of High Energy Physics of Chinese Academy of Science.